A Abbreviations

APC Avarage Product Correction

CASP Critical Assessment of protein Structure Prediction

CD Contrastive Divergence

DCA Direct Coupling Analysis

DI Direct Information

EM electron microscopy

MAP Maximum a posteriori

MCMC Markov Chain Monte Carlo

MI mutual information

ML Maximum-Likelihood

MLE Maximum-Likelihood Estimate

MRF Markov-Random Field

MSA Multiple Sequence Alignment

Neff Number of effective sequences

PCD Persistent Contrastive Divergence

PDB protein data bank

SGD stochastic gradient descent